Electrosprayed edible microcarriers based on gelatin-coated alginate for muscle cell culture
27 September 2026 · Electrohydrodynamics and Fluid Dynamics · Electrospun Nanofibers in Biomedical Applications · Mass Spectrometry Techniques and Applications
Gelatin-coated alginate microcarriers supported muscle cell culture in static and agitated systems, suggesting an edible scaffold for cultivated meat production. Researchers electrosprayed spherical, 242 µm alginate particles, coated them with gelatin, and seeded them with mouse myoblasts and immortalised bovine satellite cells at two densities for seven days. Both cell types remained viable and proliferated under static conditions, with metabolic activity similar to 2D cultures. Agitation slightly reduced proliferation, but metabolic activity and carrier structure remained stable. The early shake-flask evidence warrants further scale-up testing.